Prospective evaluation of FISH for detecting upper tract urothelial carcinoma in voided urine specimens

Fluorescence in situ hybridization status of voided urine predicts invasive and high-grade upper tract urothelial carcinoma

Here, we assessed the diagnostic accuracy of fluorescence in situ hybridization (FISH) for detecting aggressive upper tract urothelial carcinoma (UTUC). A total of 210 UTUC patients from a single hospital in China were enrolled in this retrospective study between 2012 and 2016. Patients were classified as FISH-positive or -negative based on FISH analysis of voided urine, and the clinicpathologi...

Diagnosis and Evaluation of Upper Tract Urothelial Carcinoma (UTUC)

Management of Upper Tract Urothelial Carcinoma

Upper tract urothelial carcinoma (UTUC) of the kidney and ureter is a rare neoplasm with roughly 3000 cases diagnosed in the United States in 2007, compared to approximately 67000 cases of bladder cancer. UTUC accounts for approximately 10% of cancers arising from the kidney and less than 5% of all urothelial malignancies. Predominantly due to the rarity of the disease, there is only limited da...

Endoscopic Management of Upper Tract Urothelial Carcinoma

Nephroureterectomy is currently the gold standard for management of upper urinary tract urothelial carcinoma despite it results. This review article in the loss of a renal unit. The ultimate aim of endoscopic management of this condition is cancer control whilst preserving renal function and the integrity of the urinary tract. Endoscopic treatments of upper tract TCC include the antegrade percu...

Comprehensive Management of Upper Tract Urothelial Carcinoma

Urothelial carcinoma of the upper urinary tract represents only 5% of all urothelial cancers. The 5-year cancer-specific survival in the United States is roughly 75% with grade and stage being the most powerful predictors of survival. Nephroureterectomy with excision of the ipsilateral ureteral orifice and bladder cuff en bloc remains the gold standard treatment of the upper urinary tract uroth...